HEMATOLOGICAL MALIGNANCIES

This study tests a new drug called teclistamab for people with multiple myeloma that has come back or stopped responding to other treatments. The drug is designed to help the immune system attack cancer cells. About 194 participants will receive the drug to see if it shrinks tumo…

This study tests an experimental drug called AZD9829 in people with blood cancers (like leukemia) that have a specific marker called CD123. The drug is given through a vein, alone or with other medicines. The main goals are to find a safe dose and to see what side effects occur. …

This early-stage study tests an oral drug called MK-1026 in 12 Chinese adults with blood cancers (like lymphoma or leukemia) that returned or didn't respond to prior therapies. The main goals are to check the drug's safety and how the body processes it. Researchers will also look…

This early-stage study tests a new drug called teclistamab in people with multiple myeloma that has returned or stopped responding to other treatments. The main goal is to find a safe dose and check for side effects. About 300 participants will receive the drug to see how well it…

This early-stage study tests a new drug, talquetamab, in people with multiple myeloma that has come back or stopped responding to other treatments. The drug works by helping the immune system attack cancer cells. The main goals are to check safety and find the best dose. About 27…

This study is testing two immunotherapy drugs, durvalumab and tremelimumab, in children and teens up to age 17 with advanced solid tumors or blood cancers that have not responded to standard treatments. The first part finds the safest dose, and the second part checks if the drugs…

This study looks at whether weighted blankets can improve sleep in adults with blood cancers. Twenty participants will use the blankets, and researchers will track any side effects and changes in sleep quality. The goal is to see if this simple, non-drug approach is safe and help…

This study looked at whether relaxation breathing exercises can help manage nausea and vomiting caused by chemotherapy in people with blood cancers. Sixty-eight patients took part, with half doing breathing exercises three times a day plus standard care, and the other half receiv…

This study was designed to track how the immune system recovers after CAR-T cell therapy and to test a pneumococcal vaccine (PCV-21) in these patients. It planned to enroll 50 adults with blood cancers or solid tumors. However, the study was withdrawn before any participants were…