New antibody drug shows promise for Hard-to-Treat blood cancer

NCT ID NCT03145181

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 28 times

Summary

This early-stage study tests a new drug, teclistamab, in about 300 people with multiple myeloma (a type of blood cancer) that has returned or stopped responding to standard treatments. The main goal is to find a safe dose and check for side effects. Teclistamab works by helping the immune system attack cancer cells.

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Contacts and locations

Locations

  • CHRU Tours Hopital Bretonneau

    Tours, 37044, France

  • City of Hope

    Duarte, California, 91010, United States

  • Clinica Univ. de Navarra

    Pamplona, 31008, Spain

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • Haematology Centre, R 51

    Stockholm, SE-141 86, Sweden

  • Hosp Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hosp Clinico Univ de Salamanca

    Salamanca, 37007, Spain

  • Hosp. Univ. Germans Trias I Pujol

    Badalona, 08916, Spain

  • Hospices Civils de Lyon HCL

    Lyon, 69002, France

  • Icahn School of Medicine at Mount Sinai Program for the Protection of Human Subjects

    New York, New York, 10029, United States

  • Levine Cancer Institute

    Charlotte, North Carolina, 28204, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • VU Medisch Centrum

    Amsterdam, 1081 HV, Netherlands

Conditions

Explore the condition pages connected to this study.