HEMATOLOGIC MALIGNANCY
Clinical trials for HEMATOLOGIC MALIGNANCY explained in plain language.
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New drug shows promise in preventing Graft-Versus-Host disease
Disease control CompletedThis early study tested the drug belimumab (Benlysta) to see if it could prevent chronic graft-versus-host disease (GvHD) in 10 adults who had a stem cell transplant for blood cancer. GvHD is a serious condition where the donor's immune cells attack the patient's body. The main g…
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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Blood cancer drug besponsa under safety watch in korea
Disease control CompletedThis study monitored the safety and effectiveness of Besponsa, a drug for relapsed or refractory B-cell acute lymphoblastic leukemia (ALL), in 108 Korean patients. Researchers tracked side effects and how well the drug worked in real-world use. The goal was to identify any new or…
Matched conditions: HEMATOLOGIC MALIGNANCY
Sponsor: Pfizer • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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New radiation technique aims to safely prepare blood cancer patients for transplant
Disease control CompletedThis study tested a new way to deliver total body radiation to adults with blood cancers who need a stem cell transplant. The goal was to see if this method could effectively target cancer while protecting the lungs. 36 patients took part, and the study focused on safety and how …
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: NA • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 09, 2026 12:09 UTC
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New drug may ease severe skin rashes in cancer patients
Symptom relief CompletedThis study tested whether the drug benralizumab can safely reduce skin rashes caused by cancer treatments like checkpoint inhibitors. The goal was to lower the number of certain white blood cells (eosinophils) to calm the rash, improve quality of life, and allow patients to keep …
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jun 16, 2026 12:54 UTC
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Blood transfusions unlock hospice access for blood cancer patients
Symptom relief CompletedThis study tested a new way to help people with blood cancers (like leukemia or lymphoma) get into hospice care earlier. Normally, hospice doesn't cover blood transfusions, so patients delay hospice to keep getting them. The study paid for transfusions while patients were on hosp…
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: NA • Sponsor: Adam Olszewski • Aim: Symptom relief
Last updated Jun 15, 2026 19:04 UTC
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Bringing blood transfusions home: a new option for advanced cancer patients?
Symptom relief CompletedThis study looked at whether giving blood transfusions at home is possible and acceptable for people with advanced blood cancers who need regular transfusions. Ten patients took part, and researchers measured how many agreed to join, how many completed home transfusions, and how …
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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HIIT and weights show promise for stem cell recovery
Symptom relief CompletedThis study looked at whether 12 weeks of high-intensity interval training (HIIT) and resistance training could help people who had a stem cell transplant for blood cancer. It involved 16 patients and their caregivers. The goal was to see if exercise improves physical function, th…
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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Study aims to uncover hidden hormone problems in ICU patients
Knowledge-focused CompletedThis study looked at how the adrenal glands work in people who are very sick in the hospital. The goal was to better understand a condition called adrenal insufficiency, where the body doesn't make enough stress hormones. Researchers studied 225 patients and healthy volunteers to…
Matched conditions: HEMATOLOGIC MALIGNANCY
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:55 UTC
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Heart defects may worsen outcomes for childhood cancer survivors
Knowledge-focused CompletedThis study looked at 800 children who survived blood cancer to see if having a congenital heart defect raises their risk of death or other health problems later in life. Researchers also checked for shared genes between the two conditions. The goal is to better understand and pre…
Matched conditions: HEMATOLOGIC MALIGNANCY
Sponsor: Children's Hospital of Fudan University • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:51 UTC
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Study reveals vaccine response gap in immunocompromised individuals
Knowledge-focused CompletedThis study looked at how well the Pfizer COVID-19 vaccine triggers an immune response in 196 adults with weakened immune systems (like kidney transplant patients or those with cancer) compared to healthy adults. Researchers measured antibody levels and their ability to fight the …
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: PHASE4 • Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC
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COVID-19 vaccine immune response studied in vulnerable young patients
Knowledge-focused CompletedThis study looked at how well COVID-19 vaccines work in 21 children and young adults (under 24) with cancer or who had a transplant or cellular therapy. Researchers measured antibody and T-cell responses over time to understand vaccine effectiveness in these immunocompromised pat…
Matched conditions: HEMATOLOGIC MALIGNANCY
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:08 UTC
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Tiny bugs in Kids' mouths and noses may hold clues to cancer treatment risks
Knowledge-focused CompletedThis study looked at the tiny organisms (fungi and bacteria) living in the mouth and nose of 62 children with leukemia or those getting a bone marrow transplant. The goal was to see how these germs change during cancer treatment. The results may help doctors understand why some c…
Matched conditions: HEMATOLOGIC MALIGNANCY
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 05, 2026 12:08 UTC
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App vs. paper: which diary boosts cancer pill adherence?
Knowledge-focused CompletedThis study tested whether an electronic diary app helps cancer patients take their oral medications more consistently than a traditional paper diary. A total of 124 adults with solid tumors or blood cancers were randomly assigned to use either the app or a paper diary to track th…
Matched conditions: HEMATOLOGIC MALIGNANCY
Phase: NA • Sponsor: Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS • Aim: Knowledge-focused
Last updated Jun 01, 2026 18:05 UTC