Study aims to uncover hidden hormone failure in ICU patients

NCT ID NCT00156767

First seen Jun 26, 2026 · Last updated Jul 29, 2026 · Updated 7 times

Summary

This study looks at how the adrenal glands work in people who are critically ill, such as those with sepsis. Adrenal insufficiency may affect up to 77% of ICU patients, but current tests are not reliable. Researchers will measure hormone levels in 225 participants, including healthy volunteers, to develop better diagnostic methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to better diagnostic tests for adrenal insufficiency in critically ill patients, helping doctors identify and treat the condition more accurately.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve patient outcomes. Results may not change current practices without further research.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

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