Small study checks COVID-19 vaccine power in young cancer patients

NCT ID NCT05164016

Completed Knowledge-focused Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how well COVID-19 vaccines trigger an immune response in children and young adults (under 24) with cancer or who had a transplant or cellular therapy. Researchers measured antibody and T-cell levels after vaccination. The goal was to learn more about vaccine effectiveness in these vulnerable groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: COVID-19 vaccine
What this could lead to: If successful, this could help doctors understand how well COVID-19 vaccines protect immunocompromised patients and guide future vaccination strategies.
What could go wrong: This is a small, completed observational study with only 21 participants, so results may not apply to larger or different groups. It does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer disease related to transplantation hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER CELLULAR THERAPY HEMATOLOGIC MALIGNANCY HEMATOPOIETIC CELL TRANSPLANT HEMATOPOIETIC SYSTEM--CANCER SOLID ORGAN TRANSPLANT SOLID TUMOR MALIGNANCY TRANSPLANT-RELATED CANCER

Contacts and locations

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Locations

Le Bonheur

Memphis, Tennessee, 38103, United States
LeBonheur

Memphis, Tennessee, 38103, United States
St. Jude Children's Research Hospital

Memphis, Tennessee, 38105, United States

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