HEALTHY ADULTS

This study tests a new mRNA-based flu vaccine in healthy adults aged 18 and older. Participants receive one dose of either the experimental vaccine or an approved flu vaccine for comparison. The study lasts about 6 months and includes 3 visits for blood draws and a nasal swab. Th…

This early-stage study tests two experimental COVID-19 booster vaccines alongside two authorized ones in 48 healthy adults aged 18-65 who have already received at least two mRNA COVID-19 shots. The goal is to check safety and measure how well the vaccines boost the immune system.…

This early-stage study tests a new gene therapy that aims to increase levels of a protein called Klotho, which is linked to better brain function and overall health. The trial involves 24 healthy adult volunteers who will receive a single injection of the therapy. Researchers wil…

This early-stage study tests a gene therapy that delivers instructions for two proteins—klotho and follistatin—into the body using a harmless DNA carrier. The goal is to see if it's safe and can improve thinking and overall health in 30 healthy volunteers aged 50 to 80. Participa…

This study tests whether taking probiotics before and during a short overseas trip (less than 7 days) can prevent stomach issues, sleep problems, and other travel-related health problems. 46 healthy adults will be randomly assigned to receive either a probiotic or a placebo. The …

This study tests whether adding electrical stimulation or special sound beats to mirror therapy can improve leg movement in people who had a stroke at least 6 months ago. Researchers will measure muscle control, spasticity, and brain activity in 72 adults aged 20-80. The goal is …

This study in Lahore, Pakistan, will follow 60 healthy twins (identical and fraternal) for 12 weeks on a balanced diet. Researchers will measure changes in body fat and blood sugar to see how much genetics versus lifestyle influences diet outcomes. The goal is to learn how to cre…

This early-stage study tests the safety of a new drug called GS3-007a in 32 healthy Chinese adults aged 18-45. Participants receive either the drug or a placebo, and researchers monitor side effects and how the drug moves through the body. The study also checks if food affects dr…

This study tests which method is more accurate for placing dental implants: a custom-made guide or a dynamic navigation system that shows the dentist where to drill on a screen. Twenty healthy adults with at least one missing upper tooth will take part. The goal is to see which a…

This study looks at how two different passive warm-up methods—infrared heating and therapeutic massage—affect jump height, balance, and flexibility in healthy adults aged 18 to 35. One hundred participants will be randomly assigned to one of the warm-up groups or a control group.…

This study looks at how the body absorbs different versions of the experimental drug PF-08049820 in healthy adults. It checks if taking the drug with food or with another medicine that lowers stomach acid changes absorption. The study involves 24 participants and is not intended …

This study looks at whether eating pecans daily can improve metabolism, blood fats, inflammation, blood pressure, thinking skills, and gut bacteria in healthy adults aged 45 to 75. Participants will eat pecans every day for 3 months and avoid them for another 3 months, with blood…

This study looks at how people with mild multiple sclerosis adjust their walking when faced with obstacles or sudden changes, compared to healthy adults. Researchers will use motion sensors and brain activity monitors to measure these skills. The goal is to find better ways to de…

This study looks at how adults aged 18 to 65 move their eyes and body when using digital devices with different eyeglasses. Researchers will track eye and head movements during simple screen tasks. The goal is to understand how age and glasses type affect posture and gaze. No tre…

This study looks at whether strengthening your breathing muscles and taking a nitrate supplement (like the stuff in beets) can help healthy adults exercise longer in conditions that mimic high altitude. Researchers will measure how long 80 volunteers, aged 18 to 40, can cycle bef…

This early-stage study is testing a new drug called EDG-15400 in 108 healthy adults to see if it is safe and how the body handles it. Participants will receive either the drug or a placebo as a single dose or multiple doses. The goal is to gather safety information, not to treat …

This early-stage study tests a new drug called MIB-725 in 32 healthy adults aged 19 to 60. Participants receive a single dose (100 to 800 mg) and are monitored for side effects and how the drug moves through the body. The goal is to see if the drug is safe before testing it in pe…

This study tests whether 5 weeks of special breathing exercises can reduce breathlessness and improve exercise performance in healthy cyclists and triathletes. Researchers will measure breathing discomfort and oxygen use during exercise. The goal is to learn how to personalize br…

This study looks at how eating different amounts of fiber changes the chemicals in your breath. Twenty healthy adults will eat a low-fiber or high-fiber diet for three days, then switch after a break. Researchers want to find the best time to measure breath compounds and understa…