HEADACHE
Clinical trials for HEADACHE explained in plain language.
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Blood test may spot dangerous headaches in the ER
Diagnosis CompletedThis study looked at 81 people with bad headaches in the emergency room. Doctors measured a protein called S100B in their blood to see if it could tell the difference between a harmless headache and one caused by a more serious problem. The goal was to find a quick, simple way to…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 15, 2026 19:06 UTC
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Eye ultrasound may spot spinal headaches early
Diagnosis CompletedThis study looked at whether measuring the optic nerve sheath with ultrasound can help predict headaches after spinal anesthesia. Researchers measured the nerve sheath in 176 patients undergoing knee replacement surgery. The goal was to see if this measurement could identify who …
Matched conditions: HEADACHE
Sponsor: Ankara City Hospital Bilkent • Aim: Diagnosis
Last updated Jun 12, 2026 12:03 UTC
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Nasal nerve block offers quick headache relief after spinal needle accident
Symptom relief CompletedThis study tested whether a nasal nerve block (sphenopalatine ganglion block) could ease severe headaches that sometimes happen after accidental spinal needle puncture during epidural procedures. 26 adults were randomly assigned to receive either the nerve block or standard care …
Matched conditions: HEADACHE
Phase: NA • Sponsor: ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" • Aim: Symptom relief
Last updated Jun 16, 2026 12:49 UTC
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ER migraine study: does a simple IV drip ease Kids' pain?
Symptom relief CompletedThis study looked at whether giving children with migraine an IV of salt water (a common fluid) in the emergency room can help reduce their headache pain. 46 children took part. The goal was to see if the fluid alone, without any other medicine, could make them feel better.
Matched conditions: HEADACHE
Phase: PHASE1, PHASE2 • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 16, 2026 12:48 UTC
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Can a blood pressure drug ease Veterans' Post-Concussion headaches?
Symptom relief CompletedThis study tested whether prazosin, a drug often used for blood pressure and PTSD nightmares, can reduce the frequency and severity of chronic headaches in veterans and service members who had a mild traumatic brain injury. About 89 participants received either prazosin or a plac…
Matched conditions: HEADACHE
Phase: PHASE1, PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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Acupuncture offers headache relief for women undergoing IVF
Symptom relief CompletedThis study tested whether acupuncture can help reduce headaches, stress, and emotional distress in women going through the hormone stimulation phase of IVF. 37 adult women experiencing a headache during their IVF cycle received a 30-minute acupuncture session tailored to their ne…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Yo San University of Traditional Chinese Medicine • Aim: Symptom relief
Last updated Jun 12, 2026 12:03 UTC
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Spinal tap offers hope for debilitating headaches after brain bleed
Symptom relief CompletedThis study tested whether removing some fluid from the spine (a lumbar puncture) can reduce severe headaches in people who had a brain aneurysm rupture. 74 adults with mild to moderate brain bleeds and persistent headaches took part. The approach aims to lower pressure and clear …
Matched conditions: HEADACHE
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 08, 2026 13:12 UTC
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Zapping a neck nerve eases chronic headaches in small study
Symptom relief CompletedThis study tested a treatment called pulsed radiofrequency on a nerve at the back of the head (greater occipital nerve) in 25 adults with cervicogenic headache — a headache that starts from the neck. Participants had not gotten enough relief from standard treatments like medicati…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Jun 08, 2026 13:09 UTC
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Nerve zapping eases long COVID fatigue in small trial
Symptom relief CompletedThis study tested whether vagal nerve stimulation can reduce fatigue and headaches in people with post-COVID syndrome. Eighteen adults with ongoing symptoms after COVID-19 received the treatment. Researchers measured changes in functional status and fatigue levels to see if the a…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 05, 2026 12:07 UTC
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Hands-On therapy and Brain-Body exercises show promise for Jaw-Related headaches
Symptom relief CompletedThis study looked at whether manual therapy (hands-on treatment) and a cognitive exercise therapy approach called BETY can reduce headache pain and improve quality of life in people with headaches related to temporomandibular disorder (TMD). Sixty adults aged 18 to 60 with TMD-re…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Jun 05, 2026 12:05 UTC
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Walking may reshape your brain, new study suggests
Knowledge-focused CompletedThis study looked at how walking exercise and changes in body fat relate to brain structure in 22 overweight or obese adults who also had headaches. Participants either followed a diet plus a 12-week walking program or diet alone. Brain scans and body measurements were taken befo…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Amasya University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC
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AI simplifies brain scans: patients understand more!
Knowledge-focused CompletedThis study tested whether adding a simple, AI-written summary to brain MRI reports helps adults with headaches understand the results. Over 2700 participants read fictional reports and answered questions about what they found. The goal was to see if the AI summary improved unders…
Matched conditions: HEADACHE
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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Heart drug tested as migraine shield in small trial
Knowledge-focused CompletedThis study looked at whether ivabradine, a heart medication, could prevent migraines triggered by a chemical called levcromakalim. 37 adults with migraine without aura took part. The goal was to see if ivabradine could reduce the number of migraine attacks caused by the trigger.
Matched conditions: HEADACHE
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:03 UTC