HEADACHE
Clinical trials for HEADACHE explained in plain language.
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New hope for headache sufferers: 60-Day nerve zap study launches
Symptom relief Not yet recruitingThis study will follow 300 adults who are already scheduled to receive a temporary 60-day nerve stimulation treatment for their chronic headaches. The treatment uses a small device to stimulate nerves at the back of the head. Researchers want to see if it reduces headache impact …
Matched conditions: HEADACHE
Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 15, 2026 19:04 UTC
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Could a lidocaine shot in the head stop chronic migraines?
Symptom relief Not yet recruitingThis study tests if injecting the numbing medicine lidocaine into two brain arteries can ease chronic, hard-to-treat migraines. About 80 adults with severe migraines will receive either the injection or a placebo, and researchers will track changes in headache impact over time. T…
Matched conditions: HEADACHE
Phase: PHASE2 • Sponsor: Daniel A Tonetti, MD • Aim: Symptom relief
Last updated Jun 12, 2026 12:05 UTC
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Scientists investigate if amylin analogue sparks migraines
Knowledge-focused Not yet recruitingThis study looks at whether pramlintide, a drug similar to the hormone amylin, can cause migraine attacks in people who get migraines without aura. Researchers will give 21 participants either pramlintide or a placebo and watch for headaches over 12 hours. The goal is to understa…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC