GLIOBLASTOMA MULTIFORME

This study tested a vaccine called VBI-1901 in 70 people with recurrent glioblastoma, an aggressive brain cancer. The goal was to find the safest and most effective dose by monitoring side effects and immune responses. The trial was terminated early, so results are limited.

This early-stage study tested a new radioactive drug called 177Lu-FF58 in 24 adults with advanced pancreatic, stomach, or brain cancers that had spread or come back. The main goal was to check the drug's safety and find the right dose. The study was stopped early, so results are …

This study tested a new drug called VAL-083 for people with glioblastoma, an aggressive brain cancer, that had returned after standard treatments like temozolomide and bevacizumab. The goal was to see if VAL-083 could help patients live longer compared to other chemotherapy optio…

This study tested a new radioactive dye called [68Ga]-FF58 to see how well it lights up certain cancers on PET scans. The dye targets specific proteins found on some brain, stomach, and pancreatic tumors. The study was stopped early, but the goal was to learn about the dye's safe…

This study tested whether a simple spinal fluid sample (liquid biopsy) can detect tumor DNA in children and young adults with brain tumors. Researchers compared DNA from spinal fluid with DNA from tumor tissue to see if the fluid test could replace surgery. No treatment was given…

This early-phase study tested whether ketoconazole, a drug used for fungal infections, can enter glioblastoma brain tumors in high enough amounts to stop cancer cells from dividing. Only one adult with a high-grade glioma was enrolled before the study was terminated. The goal was…

This early-stage study tested whether posaconazole, a drug normally used for fungal infections, can reach high enough levels in brain tumors to stop cancer cells from dividing. Seven adults with glioblastoma took the drug before surgery to have their tumor removed. The goal was t…