GIST
Clinical trials for GIST explained in plain language.
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New combo therapy targets advanced GIST in early trial
Disease control Recruiting nowThis study tests a new drug called DCC-3116 combined with other cancer treatments for people with advanced GIST, a type of stomach or intestinal cancer. About 94 adults whose cancer has worsened after standard treatment will join. The goal is to find safe doses and see if the com…
Matched conditions: GIST
Phase: PHASE1, PHASE2 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated May 17, 2026 04:12 UTC
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New hope for kids with tough cancers: radioactive therapy trial launches
Disease control Recruiting nowThis study tests a radioactive drug (lutetium Lu 177 edotreotide) in children aged 2 to 17 with cancers that have a specific marker (SSTR-positive). The goal is to find the best dose and see if it is safe. About 20 children whose cancer has not responded to prior treatment will t…
Matched conditions: GIST
Phase: PHASE1 • Sponsor: ITM Solucin GmbH • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New study seeks best endoscopic method for stomach tumors
Disease control Recruiting nowThis study compares two minimally invasive procedures to remove small stomach tumors called GISTs. About 136 adults with tumors between 1 and 3.5 cm will be randomly assigned to one of two endoscopic techniques. The goal is to see which method removes the entire tumor more comple…
Matched conditions: GIST
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated May 12, 2026 13:44 UTC
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New hope for stomach cancer patients Who've run out of options?
Disease control Recruiting nowThis study tests the drug lenvatinib in people with advanced gastrointestinal stromal tumors (GIST) that have stopped responding to three standard treatments. The goal is to see if lenvatinib can shrink or stabilize the tumors and to check for side effects. About 48 adults will t…
Matched conditions: GIST
Phase: PHASE1, PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
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New hope for GIST: experimental combo targets hard-to-treat tumors
Disease control Recruiting nowThis study tests whether adding an experimental drug (KQB198) to the standard cancer pill imatinib is safe and works better for people with advanced gastrointestinal stromal tumor (GIST). About 46 adults whose cancer has spread and who have not yet received treatment for advanced…
Matched conditions: GIST
Phase: PHASE2 • Sponsor: Kumquat Biosciences Inc. • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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Hunt for hidden cancer genes: 1,500 families join landmark study
Knowledge-focused Recruiting nowThis research study aims to discover new genes that may cause cancer to run in families. Researchers will collect blood samples and health information from 1,500 people in families where multiple members have had childhood cancers. Participants will not receive direct treatment o…
Matched conditions: GIST
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 04:25 UTC