GIST
Clinical trials for GIST explained in plain language.
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New hope for rare stomach cancer: drug combo targets tough mutations
Disease control OngoingThis study compares two drugs, ripretinib and sunitinib, in people with advanced gastrointestinal stromal tumors (GIST) that have specific genetic changes (KIT exon 11 plus 17/18 mutations) and have stopped responding to the first treatment, imatinib. About 54 participants will b…
Matched conditions: GIST
Phase: PHASE3 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New hope for drug-resistant GIST: combo therapy targets stubborn tumors
Disease control OngoingThis study tests a new two-drug combination (bezuclastinib plus sunitinib) in 40 adults with advanced gastrointestinal stromal tumors (GIST) that grew while on sunitinib alone. The goal is to see if the combo can slow cancer progression and understand why some tumors resist treat…
Matched conditions: GIST
Phase: PHASE2 • Sponsor: Sarcoma Alliance for Research through Collaboration • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC