GIST
Clinical trials for GIST explained in plain language.
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New combo therapy offers hope for patients with resistant stomach cancer
Disease control OngoingThis study tests a new drug combination (bezuclastinib plus sunitinib) in 40 adults with advanced gastrointestinal stromal tumors (GIST) that worsened despite sunitinib treatment. The goal is to see if the combination can delay cancer growth. Participants take both drugs by mouth…
Matched conditions: GIST
Phase: PHASE2 • Sponsor: Sarcoma Alliance for Research through Collaboration • Aim: Disease control
Last updated May 17, 2026 04:27 UTC
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New hope for rare stomach cancer: targeted drug tested against standard therapy
Disease control OngoingThis study tests a new drug, ripretinib, against the current standard sunitinib in people with advanced GIST (a rare stomach and gut cancer) whose tumors have specific genetic changes and have stopped responding to the first treatment, imatinib. About 54 adults will be randomly a…
Matched conditions: GIST
Phase: PHASE3 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated May 12, 2026 13:44 UTC