New hope for GIST: experimental combo targets hard-to-treat tumors

NCT ID NCT07406633

First seen Feb 21, 2026 · Last updated May 07, 2026 · Updated 7 times

Summary

This study tests whether adding an experimental drug (KQB198) to the standard cancer pill imatinib is safe and works better for people with advanced gastrointestinal stromal tumor (GIST). About 46 adults whose cancer has spread and who have not yet received treatment for advanced disease will take the combination. The main goal is to see if tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.