Kumquat Biosciences Inc.

This early-stage trial tests a new drug called KQB548 in people with advanced solid tumors (like pancreatic, colorectal, or lung cancer) that have a specific genetic change called KRAS G12D. The main goals are to find a safe dose and see if the drug can shrink tumors. About 78 pa…

This early-phase study tests a new drug called KQB365 in adults with advanced solid tumors (like colorectal cancer) that have specific KRAS mutations (G12C or G12S). The main goals are to find a safe dose and see if the drug can shrink tumors when given alone or with other cancer…

This early-phase trial tests a new drug called KQB198 in adults with advanced solid tumors that have certain genetic changes. The study aims to find safe doses of KQB198 alone or with other cancer drugs, and to see if it can shrink tumors. About 100 participants will take the dru…

This early-stage study tests a new daily pill, KQB168, alone or with another drug (pembrolizumab) in adults with advanced solid tumors that have stopped responding to immunotherapy. The main goals are to find a safe dose and see if the drug can shrink tumors. About 84 participant…

This study tests whether adding an experimental drug (KQB198) to the standard cancer pill imatinib is safe and works better for people with advanced gastrointestinal stromal tumor (GIST). About 46 adults whose cancer has spread and who have not yet received treatment for advanced…