GIST
Clinical trials for GIST explained in plain language.
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New combo therapy targets hard-to-treat GIST tumors
Disease control Recruiting nowThis study tests a new drug called DCC-3116 combined with other cancer treatments for people with advanced GIST, a type of stomach or intestinal cancer. The goal is to find safe doses and see if the combination shrinks tumors. About 94 adults whose cancer has worsened after stand…
Matched conditions: GIST
Phase: PHASE1, PHASE2 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New hope for GIST: experimental combo targets hard-to-treat tumors
Disease control Recruiting nowThis study tests whether adding an experimental drug (KQB198) to the standard cancer pill imatinib can shrink or control advanced gastrointestinal stromal tumors (GIST). About 46 adults with a specific gene mutation (KIT or PDGFRA) will receive the combination. The goal is to see…
Matched conditions: GIST
Phase: PHASE2 • Sponsor: Kumquat Biosciences Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New hope for kids with tough cancers: targeted radiation trial launches
Disease control Recruiting nowThis early-stage trial tests a radioactive drug (Lu-177 edotreotide) in children aged 2 to 17 with cancers that have a specific marker (SSTR-positive). The goal is to find the right dose and check safety. About 20 children whose cancer has returned or not responded to prior treat…
Matched conditions: GIST
Phase: PHASE1 • Sponsor: ITM Solucin GmbH • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New hope for stomach cancer patients Who've tried everything?
Disease control Recruiting nowThis study tests the drug lenvatinib in 48 adults with advanced gastrointestinal stromal tumors (GIST) that have stopped responding to three standard treatments. Participants take lenvatinib capsules daily, and researchers will measure how many patients have their disease control…
Matched conditions: GIST
Phase: PHASE1, PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New study seeks best way to remove stomach tumors without major surgery
Disease control Recruiting nowThis study compares two endoscopic procedures—EFTR and STER—for removing small gastric GIST tumors (1.0–3.5 cm). About 136 adults from Hong Kong, mainland China, India, and Japan will be randomly assigned to one method. The goal is to see which technique achieves complete tumor r…
Matched conditions: GIST
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Hunt for hidden cancer genes: families needed to unlock hereditary secrets
Knowledge-focused Recruiting nowThis study aims to discover new genes that may cause certain cancers to run in families. Researchers will collect blood samples and health information from 1,500 people in families where multiple members have had cancer, especially childhood cancers. The goal is to build a regist…
Matched conditions: GIST
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC