GERM CELL TUMOR
Clinical trials for GERM CELL TUMOR explained in plain language.
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Engineered immune cells take on childhood cancers in early trial
Disease control OngoingThis early-phase study tests a personalized cell therapy for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, modified to recognize and attack a protein called B…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 17, 2026 01:59 UTC
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New hope for incurable cancer? cabozantinib trial targets resistant germ cell tumors
Disease control OngoingThis study tests the drug cabozantinib in 50 adults with germ cell tumors (like testicular or ovarian cancer) that have not responded to standard chemotherapy. The goal is to see if the drug can shrink tumors or stop them from growing for at least 3 months. Participants take the …
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: Jennifer King • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Engineered immune cells take aim at childhood cancers in early trial
Disease control OngoingThis early-stage study tests a personalized cell therapy for children and young adults (ages 1–30) with solid tumors that have come back or not responded to treatment. The therapy uses the patient's own immune cells, modified to recognize and attack tumors that carry a protein ca…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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Engineered immune cells injected directly into brain show promise for kids with cancer
Disease control OngoingThis early-stage study tests whether specially engineered immune cells (CAR T cells) can be safely given directly into the brain or spinal fluid of children and young adults with HER2-positive brain tumors that have come back or not responded to standard treatments. The cells are…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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Immunotherapy duo takes on resistant germ cell cancers
Disease control OngoingThis study tests whether combining two immunotherapy drugs, durvalumab and tremelimumab, can shrink tumors in people with germ cell cancers that have come back or not responded to standard treatment. About 30 adults with measurable disease are participating. The main goal is to s…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:04 UTC
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Proton beam therapy aims to shrink brain tumors with fewer side effects
Disease control OngoingThis study looks at whether proton beam radiation can safely treat germ cell tumors in the brain and spine of people aged 3 to 25. The goal is to kill the tumor while causing fewer side effects than standard photon radiation. Researchers will track side effects and how long the t…
Matched conditions: GERM CELL TUMOR
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 04, 2026 16:21 UTC
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Blood marker may predict cancer return in testicular cancer patients
Knowledge-focused OngoingThis study is testing whether a blood marker called miRNA 371 can predict if germ cell tumors (a type of cancer) will return after treatment. Researchers are collecting blood samples from 956 newly diagnosed patients and tracking their health over time. The goal is to see if this…
Matched conditions: GERM CELL TUMOR
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Survivors of rare ovarian cancers share how chemotherapy affects their daily lives years later
Knowledge-focused OngoingThis study looks at women who have recovered from rare ovarian cancers (germ cell or sex cord-stromal tumors) to understand how chemotherapy affects their energy, heart and lung health, and overall quality of life. About 268 participants will fill out questionnaires and undergo t…
Matched conditions: GERM CELL TUMOR
Phase: NA • Sponsor: Centre Francois Baclesse • Aim: Knowledge-focused
Last updated May 07, 2026 18:40 UTC