Can freezing ovarian tissue help girls have babies later?

NCT ID NCT02646384

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study offers girls from birth to age 17 the chance to freeze their ovarian tissue before medical treatments that could harm their fertility, such as chemotherapy or radiation. The tissue is removed surgically and stored. Later, if they want to have children, the tissue can be transplanted back. The study is tracking how many pregnancies and live births result from this approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ovarian tissue cryopreservation (freezing and storage of ovarian tissue)

What this could lead to

If successful, this could help girls who need cancer treatment or other therapies to have a chance at biological children later in life.

What could go wrong

This is an early-stage experimental procedure, and it is not yet proven how often it leads to pregnancy. The tissue may not survive transplantation, and risks from surgery exist.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer germ cell tumor lupus nephritis neoplasm ovarian neoplasm Turner syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States