GERM CELL TUMOR
Clinical trials for GERM CELL TUMOR explained in plain language.
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New hope for kids with rare cancer: thalidomide combo shows promise
Disease control CompletedThis study tested a new treatment for children with a rare type of cancer called yolk sac tumor that had come back or stopped responding to standard chemotherapy. The treatment combined the drug thalidomide with three chemotherapy drugs. The goal was to see if this combination co…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: Shandong First Medical University • Aim: Disease control
Last updated May 17, 2026 02:07 UTC
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Engineered immune cells delivered directly to the brain show promise in kids with tough tumors
Disease control CompletedThis early-phase study tested a new treatment for children and young adults with brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein called EGFR fou…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New hope for kids with rare cancer: drug combo shows promise
Disease control CompletedThis study tested a new combination of drugs (sirolimus plus chemotherapy) in 32 children with a rare tumor called yolk sac tumor that had come back or not responded to standard treatment. The goal was to see if the combination could shrink tumors and help children live longer. T…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2, PHASE3 • Sponsor: Shandong First Medical University • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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New stem cell approach offers hope for kids with relapsed cancers
Disease control CompletedThis study tested a new type of stem cell transplant for children and young adults (ages 2-21) with cancers that came back or didn't respond to treatment. The approach uses a special cell filter to speed up immune recovery after transplant. The main goal was to see if the procedu…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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New T-Cell therapy explored for Hard-to-Treat germ cell tumors
Knowledge-focused CompletedThis study tested a new treatment using a patient's own modified T cells (called CAR T cells) to target a protein called CD30 on nonseminomatous germ cell tumors, a rare type of testicular cancer. Only 2 adults who had already tried at least one other treatment took part. The mai…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 02:06 UTC