GERM CELL TUMOR
Clinical trials for GERM CELL TUMOR explained in plain language.
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New hope for kids with rare, aggressive cancer after other treatments fail
Disease control CompletedThis study tested a new combination of drugs for children with a rare and aggressive cancer called yolk sac tumor, which had come back or stopped responding to standard treatments. It combined an older drug, thalidomide, with three chemotherapy drugs to see if it could shrink tum…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: Shandong First Medical University • Aim: Disease control
Last updated Apr 02, 2026 00:45 UTC
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Scientists test Direct-to-Brain immune therapy in kids with aggressive tumors
Disease control CompletedThis early-phase study tested a personalized cell therapy for children and young adults with recurrent or hard-to-treat brain tumors. Doctors collected patients' own immune cells, engineered them in a lab to target a specific protein (EGFR) on the tumor, and then delivered these …
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Immune cell therapy tested in fight against tough testicular cancers
Disease control CompletedThis study tested a personalized immune cell therapy for adults with a hard-to-treat type of testicular cancer that had come back or worsened after standard treatments. Doctors collected and modified a patient's own immune cells (T cells) to better target and attack cancer cells.…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New hope for kids with Tough-to-Treat cancer: drug combo shows promise
Disease control CompletedThis study tested whether adding the drug sirolimus to a standard chemotherapy combination could help children whose yolk sac tumors have come back or didn't respond to previous treatments. It involved 32 children under 18 who had already tried at least two other platinum-based c…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2, PHASE3 • Sponsor: Shandong First Medical University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for kids with tough cancers: Two-Step transplant trial
Disease control CompletedThis early-stage study tested a new two-step stem cell transplant method for children and young adults whose cancers had returned or didn't respond to standard treatments. The goal was to see if this approach, which uses specially processed cells from a partially matched family d…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC