GASTROPARESIS

This study tests two procedures—G-POEM and a gastric electrical stimulator—for people with severe gastroparesis (stomach paralysis) that hasn't improved with medication. Forty adults will be randomly assigned to one of two groups to compare safety and symptom relief. The goal is …

This study is testing a new device called Gastric Alimetry that records the stomach's electrical activity through electrodes placed on the belly. Researchers want to see if it can reliably detect abnormal stomach rhythms in people with conditions like gastroparesis and functional…

This pilot study from Mayo Clinic tests whether using a virtual reality headset can safely ease symptoms of gastroparesis, a condition where the stomach empties too slowly. Thirty adults with gastroparesis will try VR programs with games, meditation, and relaxation exercises. The…

This study tests a procedure called per-oral pyloromyotomy (POP) to see if it helps people with gastroparesis, a condition where the stomach empties too slowly. About 100 adults who have not improved with standard treatment will be randomly assigned to either the real procedure o…

This program allows people aged 12 and older with severe stomach or gut problems, like gastroparesis, to try domperidone when standard treatments have failed. The goal is to ease symptoms such as nausea, vomiting, and severe indigestion. The drug is not FDA-approved but is availa…

This study uses MRI scans to look at the brain and upper digestive tract in people with gastroparesis and healthy volunteers. The goal is to better understand how the brain and gut interact in this condition. Researchers will compare stomach movements before and after meals. This…

This study creates a registry of people with gastroparesis—a condition where the stomach empties too slowly, causing nausea, vomiting, and pain—who have received a gastric electrical stimulation (GES) device. The goal is to collect long-term data to help researchers understand ho…

This study tests whether electrically stimulating a nerve in the ear can reach the internal vagus nerve, which controls stomach function. Researchers will measure nerve signals and stomach activity in 131 healthy volunteers and people with gastroparesis. The goal is to see if thi…

This study looks at how a device that electrically stimulates the stomach (gastric electrical stimulation) affects the vagus nerve and heart in people with gastroparesis, a condition where the stomach empties slowly. Researchers will measure heart rate variability and hormone lev…

This study looks at how the vagus nerve works in people with gastroparesis (stomach paralysis) who have a gastric electrical stimulator implanted. Researchers will use a non-invasive electrode patch on the neck to measure nerve signals and see if they relate to symptom relief. Th…

This study aimed to find out if two tests—EndoFLIP and antroduodenal manometry—could predict which patients with severe gastroparesis would benefit from a procedure called G-POEM. The plan was to measure stomach muscle activity and pressure before the procedure. However, the stud…