Scientists map nerve signals to improve gastric stimulation for stomach paralysis

NCT ID NCT04207996

Ongoing Knowledge-focused Sponsor: Indiana University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the vagus nerve works in people with gastroparesis (stomach paralysis) who have a gastric electrical stimulator implanted. Researchers will use a non-invasive electrode patch on the neck to measure nerve signals and see if they relate to symptom relief. The goal is to better understand how the therapy works, not to test a new drug or device.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: gastric electrical stimulation therapy (Enterra device)
What this could lead to: If successful, this could help doctors better understand how gastric stimulation eases gastroparesis symptoms, potentially leading to more personalized therapy.
What could go wrong: This is a small, early-stage observational study with only 40 participants. It is not testing a new treatment, so direct patient benefits are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroparesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROPARESIS

Contacts and locations

Locations

Indiana University Hosptial

Indianapolis, Indiana, 46202, United States

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