GASTROINTESTINAL NEOPLASMS

This phase 2 study tests whether avatrombopag, a drug that boosts platelet production, can safely and effectively treat persistent low platelet counts caused by chemotherapy in people with gastrointestinal cancers. About 60 adults will receive either avatrombopag or a placebo. Th…

This study tests whether adding the drug durvalumab to standard chemotherapy (FLOT) before and after surgery helps people with stomach or gastroesophageal junction cancer live longer without the cancer coming back. About 957 participants will receive either durvalumab or a placeb…

This study compares a new bipolar knife to a standard monopolar knife for removing colon growths through a scope. About 80 adults will take part to see which knife works faster and causes fewer side effects like bleeding or pain. The goal is to improve the surgery experience and …

This study follows 138 people who had surgery for esophageal cancer to see how often they experience reflux afterward. Researchers use a simple test called PEPTEST to measure stomach acid in saliva before surgery, at discharge, and 1, 3, and 6 months later. The goal is to find pa…

This study looks at whether chemotherapy slows tumor growth in people with a rare, slow-growing appendiceal cancer that has spread. About 30 participants will be randomly assigned to either receive chemotherapy or be observed, then switch after 6 months. The goal is to measure ho…