GASTROINTESTINAL NEOPLASMS
Clinical trials for GASTROINTESTINAL NEOPLASMS explained in plain language.
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Vacuum bandage may slash infection risk after GI cancer surgery
Disease control CompletedThis study tested whether using a negative pressure wound therapy device (a special vacuum bandage) for a longer time after surgery could lower the chance of wound infections in people with gastrointestinal cancer. About 290 patients took part. The goal was to see if this approac…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Phase: PHASE2, PHASE3 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New combo attack on rectal cancer: chemo plus targeted surgery shows promise
Disease control CompletedThis study looked at 180 people with rectal cancer that had spread to lymph nodes in the pelvis. One group received a three-drug chemotherapy regimen (FOLFOXIRI) followed by surgery to remove the affected lymph nodes. The other group got standard chemoradiotherapy before surgery.…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Phase: NA • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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CRISPR-Engineered immune cells take on stomach and colon cancers
Disease control CompletedThis trial tested a new approach for people with advanced gastrointestinal cancers that had stopped responding to standard treatments. Doctors removed immune cells from patients' tumors, used CRISPR gene editing to disable a gene called CISH, and then infused the modified cells b…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Intima Bioscience, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Chemo delivery method may impact sleep and depression in GI cancer patients
Knowledge-focused CompletedThis study looked at 198 adults with non-metastatic gastrointestinal cancer to see if taking chemotherapy as a pill (oral) or through a vein (IV) affects sleep quality and depression. Researchers measured sleep and mood before treatment, at 45 days, and at 90 days using standard …
Matched conditions: GASTROINTESTINAL NEOPLASMS
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Scientists track Body's reaction to cancer immunotherapy
Knowledge-focused CompletedThis study looked at 98 adults with cancers like melanoma and lung cancer who were starting immunotherapy. Researchers measured inflammatory markers in their blood to understand how the body reacts to these drugs. The goal was to find ways to better manage side effects from treat…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC