GASTROESOPHAGEAL CANCER
Clinical trials for GASTROESOPHAGEAL CANCER explained in plain language.
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Could drugs replace surgery for some stomach and colon cancers?
Disease control TerminatedThis study aimed to see if approved immunotherapy drugs (nivolumab with or without ipilimumab) could help people with early-stage colorectal or gastroesophageal cancer delay or avoid major surgery to remove their tumors. The goal was an 'organ preservation' strategy, using the dr…
Matched conditions: GASTROESOPHAGEAL CANCER
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New cancer combo enters safety testing for dozens of tumor types
Disease control OngoingThis early-stage trial is testing the safety and finding the right dose of a two-drug combination (naptumomab estafenatox and durvalumab) for people with advanced or metastatic solid tumors. It will enroll about 120 adults with one of many eligible cancer types, including breast,…
Matched conditions: GASTROESOPHAGEAL CANCER
Phase: PHASE1 • Sponsor: NeoTX Therapeutics Ltd. • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Radiation blast may supercharge cancer drugs in small trial
Disease control OngoingThis study is testing if giving targeted, high-dose radiation to cancer spots before starting immunotherapy drugs makes the drugs work better for people with advanced stomach or esophageal cancer. It's a small, early-stage safety trial for patients whose cancer has spread but is …
Matched conditions: GASTROESOPHAGEAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Mar 11, 2026 14:52 UTC
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New hope for Tough-to-Treat stomach cancers in Final-Stage trial
Disease control OngoingThis study is testing whether an experimental drug called sacituzumab tirumotecan helps people with advanced stomach or esophageal cancer live longer than the current standard treatments. It is for people whose cancer has continued to grow despite trying at least two prior drug t…
Matched conditions: GASTROESOPHAGEAL CANCER
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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Phone app aims to help cancer patients eat better during tough treatments
Symptom relief OngoingThis study is testing whether a remote support program that provides nutrition guidance is practical and helpful for people with esophageal or stomach cancer. The program uses a mobile app to help patients track their food while they are going through chemotherapy and radiation. …
Matched conditions: GASTROESOPHAGEAL CANCER
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Scans spot hidden heart damage from cancer treatment
Knowledge-focused OngoingThis study aims to find early signs of heart damage in cancer patients receiving radiation therapy to the chest. Researchers will use special heart scans and blood tests on 28 participants before, during, and after their radiation treatment. The goal is to learn how to identify p…
Matched conditions: GASTROESOPHAGEAL CANCER
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists seek clues in cancer samples to unlock better treatments
Knowledge-focused TerminatedThis study aimed to collect blood and tumor tissue samples from people with stomach or esophageal cancer. Researchers wanted to analyze these samples to understand why some cancers stop responding to immunotherapy drugs. The study was withdrawn before any participants were enroll…
Matched conditions: GASTROESOPHAGEAL CANCER
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC