GASTRO ESOPHAGEAL REFLUX

This study tests a new procedure called Anti-Reflux Endoscopic Therapy using argon plasma coagulation (ARAT) for people with chronic gastroesophageal reflux disease (GERD). Participants must have had heartburn or acid reflux at least twice a week for 6 months and have a positive …

This study compares two surgical approaches for treating severe obesity in people who also have acid reflux (GERD). About 560 participants will be randomly assigned to receive either a newer Nissen-Sleeve procedure or the standard Roux-en-Y gastric bypass. The main goal is to see…

This study looks at whether problems with how the stomach and esophagus move can increase the risk of breathing food or liquid into the lungs (aspiration) in children with brain-related disabilities. The researchers are comparing two medicines—prucalopride and famotidine—over 10 …

This study is a registry that gathers information from medical records and patient visits about endoscopic bariatric therapies (EBTs), which are non-surgical procedures for weight loss. It includes up to 9,999 adults who have had or plan to have an EBT. The goal is to learn how w…

This study aims to find out how many children in the Czech Republic, aged 8-9 and 12-13, have symptomatic gastroesophageal reflux disease (GERD). Researchers will recruit 1,000 children through schools and ask them to complete an online questionnaire about reflux symptoms. Those …

This study aims to collect data from 40 healthy adults aged 18-85 to establish normal ranges for two new, FDA-approved tests (EndoFLIP and mucosal integrity) that assess the esophagus and stomach during an upper endoscopy. Participants must have no history of reflux, smoking, or …

This study is testing a wearable device called C-mo System that can automatically detect and describe coughs. About 300 people aged 2 and older with cough-related conditions will wear the device for 24 hours and keep a diary. The goal is to see how well the device works compared …