New surgery may control reflux as well as standard bypass in obese patients
NCT ID NCT07158008
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 36 times
Summary
This study compares two weight-loss surgeries—Nissen-Sleeve Gastrectomy (N-SG) and Roux-en-Y Gastric Bypass (RYGB)—in 560 people with severe obesity and acid reflux (GERD). The goal is to see if N-SG controls reflux symptoms as well as RYGB one year after surgery. Both procedures aim to help patients lose weight and reduce reflux, but N-SG preserves more natural digestion. The results could help doctors choose the best surgery for each patient.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Szpital Uniwersytecki w Krakowie
RECRUITINGKrakow, 30-688, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nissen-Sleeve Gastrectomy (N-SG) and Roux-en-Y Gastric Bypass (RYGB) surgical procedures
What this could lead to
If successful, this could show that a newer, less-altering surgery (N-SG) controls reflux as well as the standard bypass, giving patients more surgical options.
What could go wrong
This is a mid-stage trial with 560 participants, so results may not apply to everyone. Both surgeries carry risks like infection, nutritional issues, or complications.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.