GASTRO ESOPHAGEAL REFLUX

This study tests a new endoscopic procedure called anti-reflux mucosal ablation (ARAT) for people with chronic GERD. The procedure uses argon plasma coagulation to treat the lining of the stomach near the esophagus. 36 participants will be randomly assigned to receive either the …

This study compares two weight-loss surgeries—Nissen-Sleeve Gastrectomy (N-SG) and Roux-en-Y Gastric Bypass (RYGB)—in 560 people with severe obesity and acid reflux (GERD). The goal is to see if N-SG controls reflux symptoms as well as RYGB one year after surgery. Both procedures…

This study tests whether surgically closing the hiatal opening can control gastroesophageal reflux disease (GERD) in people with early-stage disease. Researchers will enroll 40 adults aged 18-50 with a small hiatal defect and confirmed acid reflux. The main goal is to see if the …

This study looks at whether problems with how the stomach and esophagus move increase the risk of aspiration (food or liquid going into the lungs) in children with brain-related disabilities. It compares two drugs, prucalopride and famotidine, to see which better reduces symptoms…

This study collects information from medical records and patient visits to see how well endoscopic bariatric therapies (EBTs) work for weight loss and if they are safe. It includes adults who have had or plan to have an EBT within six months. The goal is to track weight changes a…

This study aims to find out how many children in the Czech Republic, aged 8-9 and 12-13, have symptomatic gastroesophageal reflux disease (GERD). Researchers will recruit 1,000 children through schools and ask them to complete an online questionnaire about reflux symptoms. Those …

This study is testing a wearable device called C-mo that automatically detects and analyzes coughs. About 300 people aged 2 and older with chronic cough from conditions like asthma or COPD will wear the device for 24 hours. The goal is to see how accurately the device can count c…

This study aims to collect normal measurements from the esophagus and stomach in 40 healthy adults aged 18-85. Participants will undergo two quick, FDA-approved tests during a standard upper endoscopy to measure muscle function and tissue health. The data will help doctors better…

This study is creating a large database to compare two ways of taking tissue samples from the esophagus: standard forceps biopsies and a brush-based method called WATS3D. Researchers want to see if the brush method helps doctors find Barrett's esophagus or early warning signs of …