Brush vs. forceps: which biopsy method spots esophageal problems better?

NCT ID NCT04312633

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is creating a large database to compare two ways of taking tissue samples from the esophagus: standard forceps biopsies and a brush-based method called WATS3D. Researchers want to see if the brush method helps doctors find Barrett's esophagus or early warning signs of cancer more often. Up to 90,000 adults with heartburn or known esophageal conditions will take part.

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Conditions

The condition(s) this trial relates to.

Barrett esophagus esophageal disorder esophagus carcinoma in situ gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Ambulatory Care

    RECRUITING

    Bethpage, New York, 11714, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••