Glowing dye could reveal invisible cancer clues in the esophagus
NCT ID NCT07643727
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a fluorescent tracer called WGA-800CW can make precancerous or cancerous cells in Barrett's esophagus glow during endoscopy. The tracer is sprayed onto the esophagus, and special cameras detect the glow. The goal is to find the best dose and see if this method can spot dysplasia that standard scopes miss. About 49 adults with Barrett's esophagus will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- WGA-800CW (a fluorescent tracer made from wheat germ agglutinin)
- What this could lead to
- If successful, this imaging technique could help doctors find precancerous spots in Barrett's esophagus that are invisible under standard endoscopy, enabling earlier treatment.
- What could go wrong
- This is an early pilot study with only 49 participants, so results may not apply to everyone. The tracer is sprayed directly onto the esophagus, and its safety and effectiveness are still being tested.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Medical Center Groningen
Groningen, Provincie Groningen, 9713 GZ, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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