Surgical fix for heartburn? new trial tests hiatal closure

NCT ID NCT06280664

Recruiting now Disease control Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether surgically closing the hiatal opening can control gastroesophageal reflux disease (GERD) in people with early-stage disease. Researchers will enroll 40 adults aged 18-50 with a small hiatal defect and confirmed acid reflux. The main goal is to see if the procedure alone can stop GERD, measured by pH testing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical procedure (hiatal closure)
What this could lead to: If successful, this could offer a surgical option to control GERD without long-term medication for people with early-stage disease.
What could go wrong: This is a small, early-phase trial with only 40 participants. The procedure may not work for everyone, and surgery always carries risks like infection or complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GASTRO ESOPHAGEAL REFLUX are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRO ESOPHAGEAL REFLUX

Contacts and locations

Locations

The University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.