FECAL INCONTINENCE

This study tests whether psyllium fiber bars can help postmenopausal women with irritable bowel syndrome and diarrhea who experience accidental bowel leakage. Researchers will examine changes in gut bacteria and stool chemicals to see if fiber improves symptoms. The study involve…

This study compared two treatments for severe fecal incontinence: biofeedback (exercises to strengthen muscles) and injections of a bulking agent into the rectal wall. 275 adults with frequent accidents took part. After a month of basic care, those who didn't improve were randoml…

This study tested a new keyhole surgery (laparoscopic vaginorectopexy) in 25 women with multiple pelvic organ prolapses causing bowel problems. Researchers checked how well the surgery worked by looking at prolapse recurrence, bowel function, and quality of life up to 12 months a…

This study tested a surgery to help children who have trouble controlling both their bowel and bladder due to nerve problems. Thirty children who did not get better with other treatments had the surgery. The researchers looked at how safe the surgery was and if it improved the ch…

This completed study looked at how well the Axonics sacral neuromodulation system works for people with bladder or bowel control problems. 272 participants were tracked to see if their symptoms improved and if the device was safe. The device uses mild electrical pulses to calm ov…

This early study tested a wireless patch that uses a tiny electric current to push two drugs (neostigmine and glycopyrrolate) through the skin and into the blood. The goal is to help people with spinal cord injury have predictable bowel movements without needles. Only 2 healthy v…

This study tested a low-volume irrigation device (Qufora IrriSedo MiniGo) in 92 adults with fecal incontinence, chronic constipation, or both. Participants used the device at home to see if it improved bowel function and daily life. The goal was to find a simple, non-drug option …

This study tested whether injecting botulinum toxin (like Botox) into the rectum can reduce episodes of accidental bowel leakage and urgent bathroom needs in people with fecal incontinence. The trial involved 200 adults whose condition did not improve with standard treatments. Th…

This study looked at whether magnetic stimulation of nerves in the lower back can change how the colon moves. It included 30 people: healthy volunteers, and patients with constipation or fecal incontinence. The goal was to understand the effect, not to treat the condition.

This study looked at how sacral nerve stimulation (SNS) affects the nerves in the gut of people with fecal incontinence. Researchers collected tissue samples from 37 patients who had a stimulator implanted. They wanted to see if the stimulation changes certain nerve cells. The go…

This completed study tested whether high-resolution manometry (using many electronic sensors) can measure anorectal function better than traditional methods. It included 60 participants: people with fecal incontinence and healthy controls. The goal was to improve how doctors asse…

This study tested a new device called Fecobionics, which acts like artificial stool, to better understand and diagnose chronic constipation and fecal incontinence. Researchers studied 236 people, including patients and healthy volunteers, to see if the device can provide clearer …

This study tested two French questionnaires about sexuality in 298 women who had surgery for urinary incontinence, pelvic organ prolapse, or fecal incontinence. The goal was to see if these questionnaires accurately measure sexual function compared to an existing tool. No treatme…

This study tested a new device called Fecobionics in 35 healthy adults to better understand how defecation works. The device is inserted into the rectum and measures pressure, angle, and timing during bowel movements. The goal is to gather normal data that could help diagnose and…

This early-phase trial in 13 healthy volunteers measures how two drugs, neostigmine and glycopyrrolate, enter the bloodstream when given through a skin patch using a mild electric current (iontophoresis) compared to an IV. The goal is to see if this needle-free method could one d…