FECAL INCONTINENCE

This early study tests whether injecting a person's own muscle fragments into the anal sphincter can repair muscle and improve bowel control. Ten adults with severe, long-term fecal incontinence who have not been helped by other treatments will receive the injection. The goal is …

This study tests whether adding a beta-glucan moisturizing cream to standard skin care helps heal incontinence-associated dermatitis faster and reduces symptoms like pain, itching, and burning. Sixty adults with this skin condition will receive either the cream plus standard care…

This early-stage study is testing whether injecting Botox into the rectum can help children aged 4-18 who have severe, non-retentive fecal incontinence (leaking stool not caused by constipation). The 14 participants will receive one round of injections and be tracked for 15 weeks…

This study tests a simple, at-home video program that teaches people how to better control their anal and belly muscles to reduce accidental bowel leaks and improve constipation. About 96 adults with these issues will either use the video exercises or take a placebo pill. The goa…

This study tests whether doing active anal sphincter squeezes during home-based electrical stimulation works better than electrical stimulation alone for people with fecal incontinence. 24 adults with at least monthly leakage will be randomly assigned to one of two groups and use…

This early study tests a device called UCon, which is placed on the skin to send mild electrical pulses to nerves that control the bladder and bowel. The goal is to reduce symptoms like sudden urges, leaks, and frequent bathroom trips in women with overactive bladder or bowel dys…

This study tests botulinum toxin (Botox) injections into the rectum to help people with fecal incontinence who haven't improved with standard treatments. Researchers want to understand how the injections work and which patients benefit most. About 21 adults will participate, and …

This study tests whether gentle electrical stimulation of a nerve in the genital area can improve bowel control in people with spinal cord injury. Researchers will measure how the rectum and anus respond to the stimulation using a small balloon. The goal is to see if this non-inv…

This study tests a device called c-RED, which uses a balloon to provide resistance during anal muscle contractions. The goal is to see if this exercise can strengthen muscles and improve fecal incontinence. Researchers will measure anal and vaginal pressure, incontinence severity…

This study is creating a registry of up to 5,000 patients with various gut movement disorders, such as GERD, gastroparesis, and IBS. Doctors will use standard criteria to make accurate diagnoses and collect patient-reported outcomes. The goal is to improve understanding of these …

This study aims to collect electrical signals from the body in people with overactive bladder, fecal incontinence, or urinary retention who are receiving sacral neuromodulation therapy. Researchers will gather data at several time points during the evaluation period to better und…

This study uses a special device called Fecobionics, which looks and feels like real stool, to measure how the anal muscles work in healthy people and those with fecal incontinence. The goal is to better understand the condition and improve diagnosis. About 155 adults will partic…