Scientists probe how nerve zaps fix bowel leakage

NCT ID NCT01786304

Completed Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how sacral nerve stimulation (SNS) affects the nerves in the gut of people with fecal incontinence. Researchers collected tissue samples from 37 patients who had a stimulator implanted. They wanted to see if the stimulation changes certain nerve cells. The goal was to understand why SNS works, not to test if it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sacral nerve stimulation (implanted device)
What this could lead to: If successful, this could explain how sacral nerve stimulation works, potentially leading to better treatments for fecal incontinence.
What could go wrong: This is a small, early-stage study focused on understanding how the treatment works, not on proving it is effective. The results may not lead to new treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fecal Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FECAL INCONTINENCE

Contacts and locations

Locations

Nantes University Hospital

Nantes, Pays de Loire, 44000, France
Rouen University Hospital

Rouen, Normandy, 76000, France

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