Botox for bowel leaks? small study tests new hope for kids

NCT ID NCT06785844

Recruiting now Symptom relief Sponsor: Shaare Zedek Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study is testing whether injecting Botox into the rectum can help children aged 4-18 who have severe, non-retentive fecal incontinence (leaking stool not caused by constipation). The 14 participants will receive one round of injections and be tracked for 15 weeks to see if accidents become less frequent. It is a small, open-label pilot, so results are preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Botulinum toxin A (Botox)
What this could lead to: If it works, this could offer a new treatment option for children with hard-to-treat fecal incontinence.
What could go wrong: This is a very early, small pilot study with only 14 children. It is not placebo-controlled, so results may be less reliable. The treatment may not work or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fecal Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FECAL INCONTINENCE

Contacts and locations

Locations

Shaare Zedek Medical Center
RECRUITING

Jerusalem, Israel

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