FATIGUE

This early-stage study tests whether bupropion, a medicine used for smoking cessation and depression, can reduce severe tiredness in people with end-stage kidney disease on dialysis. Sixteen participants will take bupropion three times a week for 8 weeks and report their fatigue …

This study tests whether electroacupuncture (a type of acupuncture with mild electrical pulses) can reduce a group of common symptoms—pain, tiredness, sleep problems, anxiety, depression, and memory fogginess—in breast cancer survivors who are on hormone therapy. About 228 women …

This study tests whether laser acupuncture can reduce fatigue and improve quality of life in adults with end-stage kidney disease who are on dialysis. Fifty participants will receive either real laser acupuncture or a sham treatment during their regular dialysis sessions three ti…

This study looks at whether a supplement called Alpha Brain can help healthy adults think more clearly, stay alert, and feel better when they haven't had enough sleep. About 34 people will take the supplement or a placebo in random order, with no one knowing which they got. The g…

This study tests whether personalized lifestyle coaching can help emergency medicine residents manage fatigue and perform better during overnight shifts. Thirty residents will be split into two groups: one receives one-on-one coaching on sleep, nutrition, and activity, while the …

This study tests whether a smartphone app that teaches self-acupressure can help people on dialysis feel less tired and itchy and sleep better. About 70 adults who have been on dialysis for at least three months will be randomly assigned to use the app daily for four weeks or to …

This study tests whether modafinil, a drug that promotes wakefulness, can reduce severe fatigue in people with Crohn's disease or ulcerative colitis. About 70 adults with long-term fatigue will receive either modafinil or a placebo for 12 weeks. The main goal is to see if a large…

This study looks at whether doing art activities (like painting or drawing) can help people with blood cancer feel less tired and anxious, and improve their quality of life. About 52 adults getting chemotherapy will take part. Half will do art sessions three times a week for two …