FAMILIAL HYPERCHOLESTEROLEMIA
Clinical trials for FAMILIAL HYPERCHOLESTEROLEMIA explained in plain language.
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New pill could tame inherited high cholesterol
Disease control CompletedThis study tested a new drug called MK-0616 in 303 adults with a genetic condition that causes very high cholesterol (heterozygous familial hypercholesterolemia). Participants took either the drug or a placebo for 24 weeks to see if it safely lowered their LDL (bad) cholesterol. …
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 17, 2026 07:07 UTC
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New RNA drug shows promise for Hard-to-Treat cholesterol disorders
Disease control CompletedThis early-stage study tested a new medicine called ARO-ANG3 in 93 healthy adults and people with high cholesterol or high triglycerides. The main goal was to see if the drug is safe and how the body processes it. This is a first step toward a possible new treatment for lipid dis…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE1 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated May 17, 2026 07:06 UTC
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Can a special diet plus supplements tame inherited high cholesterol?
Disease control CompletedThis pilot study tested whether a Brazilian heart-healthy diet, with or without added plant sterols or krill oil, could improve cholesterol levels in 58 adults with familial hypercholesterolemia (inherited high cholesterol). Participants followed the diet for 120 days while takin…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: NA • Sponsor: Hospital do Coracao • Aim: Disease control
Last updated May 17, 2026 06:52 UTC
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Plant-Based diet shows promise for genetic high cholesterol
Disease control CompletedThis study looked at whether a whole food plant-based diet, low in red and processed meats, can lower LDL (bad) cholesterol in adults with heterozygous familial hypercholesterolemia (HeFH), a genetic condition that causes high cholesterol. Fifty participants followed either a pla…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: NA • Sponsor: Laval University • Aim: Disease control
Last updated May 17, 2026 06:51 UTC
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New cholesterol pill shows promise in major trial
Disease control CompletedThis study tested a new medicine called MK-0616 in about 2,900 adults with high cholesterol. The goal was to see if it could safely lower bad (LDL) cholesterol more than a placebo. Participants took the drug or a dummy pill for 24 weeks, and researchers measured cholesterol chang…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New Cholesterol-Lowering pill shows promise in major trial
Disease control CompletedThis study tested a new drug called obicetrapib in over 2,500 adults with very high cholesterol or heart disease whose cholesterol was not well-controlled by their current medications. Participants took either the study drug or a placebo pill daily for about 6 months. The main go…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: NewAmsterdam Pharma • Aim: Disease control
Last updated May 13, 2026 16:04 UTC
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New combo pill slashes 'Bad' cholesterol in High-Risk patients
Disease control CompletedThis phase 3 study tested a daily pill that combines two drugs, obicetrapib and ezetimibe, to lower LDL (bad) cholesterol in 407 adults with inherited high cholesterol (HeFH) or heart disease (ASCVD). Participants were already on maximum cholesterol-lowering therapy. The main goa…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: NewAmsterdam Pharma • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Hidden gene danger: heart attack patients screened for inherited high cholesterol
Diagnosis CompletedThis study tested whether offering genetic testing for familial hypercholesterolemia (an inherited form of very high cholesterol) to people hospitalized for a heart attack could help doctors diagnose the condition earlier. Researchers enrolled 140 patients under age 60 who had a …
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: NA • Sponsor: University of British Columbia • Aim: Diagnosis
Last updated May 08, 2026 12:02 UTC
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Teens and parents share feelings after learning genetic risks in new study
Knowledge-focused CompletedThis study involved 162 teens and their parents to understand how they feel emotionally and mentally after learning about genetic risks for conditions like breast cancer, Lynch syndrome, and high cholesterol that might appear in adulthood. Researchers used surveys and interviews …
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: EARLY_PHASE1 • Sponsor: Geisinger Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 07:03 UTC
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New cholesterol drug VSA003 passes first safety check in healthy people
Knowledge-focused CompletedThis early-stage study tested a single dose of VSA003 in 36 healthy Chinese adults to see if it is safe and how the body processes it. Participants had slightly high cholesterol or triglycerides. The goal was not to treat disease but to gather safety and drug-level data before mo…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE1 • Sponsor: Visirna Therapeutics HK Limited • Aim: Knowledge-focused
Last updated May 05, 2026 11:56 UTC