FAMILIAL HYPERCHOLESTEROLEMIA
Clinical trials for FAMILIAL HYPERCHOLESTEROLEMIA explained in plain language.
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Can a Plant-Based diet tame dangerous inherited cholesterol?
Disease control CompletedThis study tested whether switching to a whole food plant-based diet could lower 'bad' LDL cholesterol in adults with a genetic condition causing very high cholesterol. For the study, 50 participants stopped their cholesterol medication and tried two different diets for four week…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: NA • Sponsor: Laval University • Aim: Disease control
Last updated Apr 02, 2026 03:57 UTC
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Can diet and natural supplements tame stubborn genetic cholesterol?
Disease control CompletedThis pilot study tested whether a specific heart-healthy diet, with or without added supplements (phytosterols and krill oil), could help lower cholesterol in adults with a genetic form of high cholesterol (familial hypercholesterolemia). All 58 participants were already on stabl…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: NA • Sponsor: Hospital do Coracao • Aim: Disease control
Last updated Apr 02, 2026 03:56 UTC
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Major trial tests new hope for millions battling stubborn high cholesterol
Disease control CompletedThis large, completed Phase 3 trial tested whether a new drug called obicetrapib could help people with high cholesterol and heart disease who weren't getting enough benefit from their current medications. Over 2,500 participants took either the new pill or a placebo (a dummy pil…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: NewAmsterdam Pharma • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New cholesterol fighter enters human testing
Disease control CompletedThis was the first study in people to test the safety of an experimental drug called ARO-ANG3, which is designed to lower unhealthy cholesterol and triglyceride levels. It involved 93 healthy volunteers and patients with high cholesterol or triglycerides. The main goal was to see…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE1 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New cholesterol pill shows promise in major trial
Disease control CompletedThis large, completed Phase 3 trial tested an oral drug called MK-0616 for adults with high cholesterol, including some with a genetic form. The main goal was to see if the drug was better than a placebo at lowering 'bad' LDL cholesterol over 24 weeks. Researchers also tracked si…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New pill aims to crush stubborn cholesterol in High-Risk patients
Disease control CompletedThis study tested whether a new combination pill containing two drugs (obicetrapib and ezetimibe) could lower 'bad' cholesterol (LDL-C) more effectively than a placebo or either drug alone. It involved 407 adults with a genetic cholesterol disorder (HeFH) or established heart dis…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: NewAmsterdam Pharma • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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New drug shows promise for stubborn genetic cholesterol
Disease control CompletedThis study tested whether an experimental drug called MK-0616 could lower 'bad' cholesterol (LDL-C) better than a placebo in adults with a genetic form of high cholesterol. Over 300 participants who were already on standard cholesterol medication received either the drug or a dum…
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 03, 2026 14:06 UTC
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First human test for new cholesterol drug completed
Knowledge-focused CompletedThis was a first-in-human study to check the safety and basic effects of a single dose of an experimental drug called VSA003. It involved 36 healthy Chinese adult volunteers. The main goal was to see how the body processes the drug and to monitor for any side effects.
Matched conditions: FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE1 • Sponsor: Visirna Therapeutics HK Limited • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC