Plant-Based diet may lower cholesterol in genetic heart condition
NCT ID NCT05181553
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether a whole-food plant-based diet, compared to a standard North American diet, can lower LDL cholesterol in 50 adults with heterozygous familial hypercholesterolemia (HeFH). Participants followed each diet for 28 days in a crossover design. Researchers also looked for metabolic markers of healthy eating.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
whole-food plant-based diet
What this could lead to
If successful, this could show that a plant-based diet helps lower cholesterol in people with familial hypercholesterolemia and provide a way to measure diet adherence.
What could go wrong
This is a small, completed study (50 participants) that looks at short-term effects only. Results may not apply to everyone with the condition.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Institute on nutrition and functional foods, Laval University
Québec, Quebec, G1V0A6, Canada