EXTUBATION FAILURE

This study compares a new type of breathing device (biphasic cuirass ventilator) to standard non-invasive ventilation in 50 high-risk patients who are about to have their breathing tube removed. The goal is to see if the new device can reduce the number of patients who need to be…

This trial tests whether measuring a patient's cough strength before removing a breathing tube can predict who will need the tube put back in. Researchers will use a special algorithm that accounts for whether the patient can cough on command or only reflexively. The goal is to g…

This study looks at newborns in the NICU who have been on a breathing machine (ventilator) for at least 48 hours. The goal is to see if heart and lung ultrasounds, along with a blood test for a specific molecule, can predict whether a baby will successfully breathe on their own a…

This study looks at whether measuring the electrical activity of the diaphragm can help doctors decide the best time to remove a breathing tube from premature babies. Researchers will track diaphragm signals and breathing patterns in 20 infants born before 32 weeks. The goal is t…

This study tests a bedside tool called the APEX score, which evaluates swallowing biomechanics, to predict whether critically ill patients will need their breathing tube reinserted after planned removal. Researchers will enroll 800 adults on ventilators for at least 48 hours acro…

This study watches 150 adults having planned surgery to see if combining three monitoring checks—breathing pattern, muscle strength, and brain activity—can better predict when it's safe to remove the breathing tube. Doctors will record these checks before removing the tube and wa…

This study looks at whether giving patients one extra hour of breathing support from a ventilator, after they pass a breathing test, helps them stay off the machine for good. About 4,000 ICU adults who have been on a ventilator for more than 72 hours will be randomly assigned to …

This study looks at whether giving critically ill patients one more hour of breathing support from a ventilator, after they pass a breathing test, can reduce the chance they need to be put back on the ventilator within a week. About 4,000 adults in intensive care who have been on…