EXTREME PREMATURITY
Clinical trials for EXTREME PREMATURITY explained in plain language.
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Premature baby brain drug fails in large trial
Disease control CompletedThis Phase 3 trial tested whether giving erythropoietin (Epo) soon after birth could reduce death or severe disability in extremely premature infants (born at 24-27 weeks). Over 900 babies were enrolled and followed until age 2. Unfortunately, Epo did not significantly lower the …
Matched conditions: EXTREME PREMATURITY
Phase: PHASE3 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Could a common painkiller help preterm Babies' hearts?
Disease control CompletedThis study tested whether giving acetaminophen (a common pain and fever medicine) to extremely preterm babies within the first 12 hours after birth can help close a blood vessel in the heart that normally closes on its own. The trial involved 804 babies born between 23 and 28 wee…
Matched conditions: EXTREME PREMATURITY
Phase: PHASE2, PHASE3 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New technique may spare tiniest babies from breathing tubes
Disease control CompletedThis study tested a method called LISA (Less Invasive Surfactant Administration) in extremely preterm infants (22-25 weeks). Instead of inserting a breathing tube, doctors gave lung medication through a thin catheter while the baby continued on CPAP. The goal was to see if this a…
Matched conditions: EXTREME PREMATURITY
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New brain monitoring method may predict injury in tiniest newborns
Knowledge-focused CompletedThis study investigates whether a non-invasive brain monitoring tool can predict brain injury in extremely low birth weight infants (≤1000 grams) during their first week of life. Researchers will measure brain blood flow using ultrasound and other sensors to see if changes in per…
Matched conditions: EXTREME PREMATURITY
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jul 02, 2026 01:00 UTC
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NICU antibiotic study questions routine use for tiniest babies
Knowledge-focused CompletedThis study looked at whether giving antibiotics early to extremely low birthweight babies (born before 31 weeks) might cause more harm than good. Researchers compared babies who got standard antibiotics to those who got a placebo. The goal was to see if early antibiotics increase…
Matched conditions: EXTREME PREMATURITY
Phase: PHASE4 • Sponsor: Michael Morowitz • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC