ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Clinical trials for ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC) explained in plain language.
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New surgical shield aims to slash leak risk in esophageal cancer patients
Disease control Not yet recruitingThis study tests a new surgical technique called ICG-OSA for people with esophageal cancer. The goal is to see if it lowers the chance of a dangerous leak where the esophagus is reconnected to the stomach. About 73 adults will get this procedure, which uses a special dye to check…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated May 17, 2026 07:08 UTC
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New protocol aims to seal deadly fistulas in esophageal cancer patients
Disease control Not yet recruitingThis study tests a standardized treatment plan for esophageal fistula, a severe complication in advanced esophageal cancer that can cause life-threatening infections and malnutrition. The plan includes sealing the fistula with stents, targeted antibiotics, nutritional support, an…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Sponsor: Peking University Cancer Hospital & Institute • Aim: Disease control
Last updated May 17, 2026 06:52 UTC
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New combo therapy aims to shrink esophageal tumors before surgery
Disease control Not yet recruitingThis study tests a new approach for people with resectable esophageal cancer. Before surgery, patients receive a short course of radiation, followed by three cycles of immunotherapy (serplulimab) plus chemotherapy. The goal is to see if this combination can eliminate or shrink th…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE2 • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated May 17, 2026 06:48 UTC
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Immunotherapy boost after chemo shows promise for tough esophageal cancer
Disease control Not yet recruitingThis phase 3 trial tests whether adding the immunotherapy drug toripalimab after standard chemoradiation helps keep advanced esophageal cancer from growing. About 340 patients whose cancer did not worsen after initial treatment will be randomly assigned to receive toripalimab or …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE3 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New combo aims to shrink esophageal tumors before surgery
Disease control Not yet recruitingThis study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy before surgery can improve outcomes for people with resectable locally advanced esophageal squamous cell carcinoma. About 390 adults aged 18-75 will be randomly assigned to receive either …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE3 • Sponsor: Tang-Du Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New hope for tough esophageal cancer: triple therapy shows promise
Disease control Not yet recruitingThis study is for people with esophageal cancer that did not shrink after initial treatment. It tests whether adding low-dose radiation to a combination of immunotherapy (toripalimab) and chemotherapy can improve outcomes. Participants will receive the new treatment, then surgery…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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New study aims to predict esophageal cancer outcomes using advanced monitoring
Knowledge-focused Not yet recruitingThis study will follow 255 people with esophageal cancer to see how the disease changes over time. Researchers will use multiple tests, including genetic analysis of tumors and blood, imaging, and immune system markers. The goal is to better predict which patients are at risk for…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Sponsor: Peking University Cancer Hospital & Institute • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC