ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Clinical trials for ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC) explained in plain language.
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Immunotherapy combo aims to extend lives in esophageal cancer
Disease control CompletedThis phase 3 trial tests whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemoradiotherapy helps people with esophageal cancer live longer and delay recurrence. About 700 participants who cannot have surgery will receive either pembrolizumab or a placeb…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Immunotherapy combo shows promise in esophageal cancer trial
Disease control CompletedThis phase 3 trial tested whether adding the immunotherapy drug tislelizumab to standard chemoradiotherapy helps people with localized esophageal squamous cell carcinoma. 370 participants received either tislelizumab or a placebo alongside chemotherapy and radiation. The study me…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE3 • Sponsor: BeiGene • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New cocktail of drugs tested for tough esophageal cancer
Disease control CompletedThis study tested several combinations of the immunotherapy drug pembrolizumab (Keytruda) with other drugs in 90 people with advanced esophageal cancer that had already progressed after one prior treatment. The goal was to see if these combinations are safe and can shrink tumors …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE1, PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New combo treatment matches standard for esophageal cancer
Disease control CompletedThis study looked at 200 people with advanced esophageal cancer to compare two treatments before surgery: immunotherapy combined with chemotherapy, versus chemotherapy plus radiation. Both treatments led to similar long-term survival rates. The immunotherapy combo may offer extra…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: NA • Sponsor: Yongtao Han • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Could more surgery and radiation after immunotherapy keep esophageal cancer at bay?
Knowledge-focused CompletedThis study looks back at medical records of people with esophageal squamous cell carcinoma who had immunotherapy and chemotherapy before surgery, followed by complete tumor removal. The goal is to see if adding radiotherapy after surgery, and how many lymph nodes were removed, af…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC