ER POSITIVE BREAST CANCER
Clinical trials for ER POSITIVE BREAST CANCER explained in plain language.
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Major trial tests promising new combo against advanced breast cancer
Disease control Recruiting nowThis large international study is testing whether a new drug called palazestrant works better than the current standard treatment when combined with another cancer drug called ribociclib. The trial will involve about 1,000 adults with advanced breast cancer that hasn't been treat…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: Olema Pharmaceuticals, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:47 UTC
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New hope for advanced breast cancer patients after standard treatments fail
Disease control Recruiting nowThis trial is testing whether a new oral medication called OP-1250 works better than current standard hormone therapies for people with advanced breast cancer that has continued to grow despite previous hormone treatments. The study will enroll about 510 adults whose cancer is ho…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: Olema Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for advanced breast cancer: testing four powerful drug combos
Disease control Recruiting nowThis early-stage study aims to find safe and effective doses for a new breast cancer drug, palazestrant, when combined with four different existing cancer drugs. It will enroll about 190 adults with advanced or metastatic ER-positive, HER2-negative breast cancer who have had limi…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE1 • Sponsor: Olema Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Three-Drug attack on breast cancer before surgery
Disease control Recruiting nowThis study is testing a combination of three drugs given to patients before breast cancer surgery. The goal is to see if this treatment can shrink tumors and potentially eliminate all detectable cancer by the time of surgery. It is for postmenopausal women with a specific type of…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Ruth O'Regan • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for Tough-to-Treat breast cancer: major trial tests powerful drug duo
Disease control Recruiting nowThis study is testing whether adding the drug everolimus to a newer hormone therapy (elacestrant) works better for controlling advanced breast cancer than the hormone therapy alone. It is for people whose cancer has a specific mutation (ESR1) and has continued to grow despite sta…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: MedSIR • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Can a 'Drug Holiday' reset treatment for tough breast cancers?
Disease control Recruiting nowThis study is for people with a specific type of advanced breast cancer that has continued to grow despite standard hormone therapy. Researchers want to see if starting one drug a month before adding a second drug is more effective than starting both together. The goal is to find…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC