ER POSITIVE BREAST CANCER
Clinical trials for ER POSITIVE BREAST CANCER explained in plain language.
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Breast cancer drug showdown trial pulled before starting
Disease control TerminatedThis study aimed to see if the drug trastuzumab deruxtecan worked better than standard CDK4/6 inhibitors for people with a specific type of advanced breast cancer (ER-positive, HER2-low, non-luminal A). The trial was withdrawn before enrolling any participants, so no results are …
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: Danish Breast Cancer Cooperative Group • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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New pill targets Cancer's 'Engine' in first human trial
Disease control OngoingThis is a first-in-human study to test the safety and find the right dose of an experimental pill called ATV-1601. It is for adults with advanced solid tumors, including certain breast, gynecologic, and prostate cancers, that have a specific genetic change called an AKT1 E17K mut…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE1 • Sponsor: Atavistik Bio, Inc • Aim: Disease control
Last updated Apr 13, 2026 20:17 UTC
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New study explores how letrozole affects breast cancer tumors before surgery
Knowledge-focused OngoingThis study looks at how the drug letrozole works in postmenopausal women with early-stage, hormone-sensitive breast cancer before they have surgery. About 178 participants will take letrozole for 4 to 24 weeks, and researchers will compare tumor samples taken before and after tre…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 08:31 UTC
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Blood test may help doctors switch cancer treatment sooner
Knowledge-focused OngoingThis study looks at whether a blood test that tracks tumor DNA can help doctors switch treatments earlier in people with stage IV breast cancer. The goal is to see if acting on this early signal can keep the cancer under control longer than waiting for scans to show growth. About…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated May 17, 2026 08:18 UTC