New drug combo shows promise in shrinking breast tumors before surgery

NCT ID NCT02562118

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of two drugs, lenvatinib and letrozole, given before surgery to postmenopausal women with a common type of breast cancer (hormone receptor positive). The goal is to see if the drugs can shrink the tumor enough to improve surgical outcomes. About 40 women will take part, first to find the safest dose, then to measure how well the treatment works.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National University Hospital

    Singapore, Singapore, 119228, Singapore

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