Can a drug holiday make breast cancer treatment work again?
NCT ID NCT05305924
First seen Jan 28, 2026 · Last updated Jun 11, 2026 · Updated 18 times
Summary
This study is for people with a common type of advanced breast cancer (ER-positive, HER2-negative) that has stopped responding to a standard treatment called a CDK4/6 inhibitor. The researchers want to see if taking a break from that drug and then switching to a different combination (fulvestrant plus abemaciclib) can help control the cancer again. About 28 participants will be enrolled to test this approach.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Houston Methodist Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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