ENDOMETRIAL CANCER

This study tested a new drug, BLU-222, for people with advanced solid tumors that had stopped responding to other treatments. The goal was to find a safe dose and see if it could shrink tumors. The study was ended early, so results are limited.

This study aimed to see if taking the drug letrozole after standard treatment could help prevent endometrial cancer from coming back. It was designed for patients whose cancer did not have a specific genetic profile. However, the trial was stopped early and only enrolled 12 peopl…

This early-stage study tested an experimental oral drug called ATX-559 in 17 people with advanced solid tumors (like breast, colon, or endometrial cancer) that had stopped responding to standard treatments. The main goal was to find a safe dose and understand side effects. The st…

This study tested a new drug called PRO1107 in 33 people with advanced solid tumors like ovarian, endometrial, and lung cancers. The goal was to check safety and see if the drug could shrink tumors. The study was stopped early, so results are limited.

This early-phase study tested an experimental pill called NKT3447 in 23 adults with advanced solid tumors (like ovarian, endometrial, or lung cancer) that had stopped responding to standard treatments. The goal was to check safety and find the right dose, but the study was termin…

This early study tested a new drug called PHN-010 in 26 people with advanced cancers like lung, colon, and ovarian cancer. The drug is designed to deliver a powerful treatment directly to cancer cells. The main goals were to check safety and find the right dose, but the study was…

This study aimed to see if a combination of two drugs, lenvatinib and pembrolizumab, could shrink tumors in Black women with a certain type of recurrent endometrial cancer. Only 4 participants were enrolled before the study was stopped early. The goal was to measure how many pati…

This study tested a new drug that delivers radiation directly to cancer cells in people with advanced solid tumors (like breast, ovarian, or head and neck cancers) that had stopped responding to standard treatments. The goal was to find a safe dose and see if it could shrink tumo…

This study looked at whether the drug niraparib could help people with advanced solid tumors (like breast, lung, or pancreatic cancer) that have a specific PALB2 gene mutation. The goal was to see if the drug could shrink tumors or slow the cancer from growing. The study was stop…

This study tested a personalized treatment where a patient's own immune cells were modified in a lab to recognize and attack unique markers on their cancer cells. It involved 8 people with advanced solid tumors like lung, pancreatic, or ovarian cancer that had not responded to st…

This study tested a combination of two drugs (copanlisib and fulvestrant) in people with advanced ovarian, endometrial, or breast cancers that are hormone receptor-positive and have certain gene changes. Only 7 people took part before the study was stopped early. The main goals w…

This study tested whether a newer, more precise radiation method called IMRT could reduce bowel and bladder side effects compared to standard 3D radiation in women who had surgery for high-risk endometrial cancer. About 92 participants were planned. The trial was stopped early, b…