EMERGENCE DELIRIUM

This trial tests whether a single dose of clonidine, given during surgery, can reduce emergence agitation—crying, thrashing, and confusion—when infants wake from anesthesia. The study includes infants aged 3 to 12 months undergoing general anesthesia with sevoflurane. Half receiv…

This study tests whether letting a child aged 2 to 6 video chat with a parent on a tablet while being taken to the operating room can reduce agitation when they wake up from anesthesia. It compares live video interaction, watching a cartoon, and standard care in 150 children havi…

This study tests whether giving magnesium before surgery can reduce emergence delirium—a state of confusion and agitation—in children aged 4 to 7 after adenotonsillectomy. Half the children receive magnesium by mouth before surgery, half receive it through an IV during surgery, a…

This study tests two different drug combinations given before anesthesia to prevent emergence delirium—a state of confusion and agitation—in children undergoing heart catheterization. Fifty children will be randomly assigned to receive either dexmedetomidine plus midazolam or ket…

This study tests whether an ultrasound-guided nerve block behind the ear can prevent agitation and confusion when children wake up from anesthesia after microscopic middle ear surgery. Researchers will compare 74 children aged 5 to 14 who receive either the nerve block or standar…

This study tests whether using positive language (like 'blow out the birthday candles') instead of standard language during anesthesia induction reduces anxiety and negative behaviors in children aged 5-10. 128 healthy children having non-emergency surgery will be randomly assign…

This study tests a simple idea: having a parent or family member involved in a child's anesthesia care to reduce emergency delirium—a state of confusion, crying, or thrashing when waking up from surgery. Researchers will compare this family-centered approach to standard care in 4…

This study compares two ways to sedate children before cleft palate repair: a combination of two drugs (dexmedetomidine and ketamine) given through a nebulizer versus dexmedetomidine alone. The goal is to see which approach works better for calming the child before surgery and pr…

This study looks at whether brain wave patterns, measured by EEG, can help explain why some children become confused and agitated after waking up from anesthesia (emergence delirium). Researchers will monitor children aged 2 to 8 who are having eye surgery under general anesthesi…

This study looks at whether the drugs used to keep you asleep during breast surgery can cause confusion or memory problems afterward. Researchers will test 200 women's thinking before and after surgery using simple puzzles and questions. The goal is to see if certain drug levels …