EARLY-STAGE BREAST CANCER
Clinical trials for EARLY-STAGE BREAST CANCER explained in plain language.
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New hope for breast cancer patients: extra targeted drug may clear remaining tumors
Disease control Not yet recruitingThis study tests whether adding 4 cycles of the targeted drug trastuzumab rezetecan (T-DXh) can eliminate residual cancer in HER2-positive breast cancer patients who still have disease after standard chemotherapy. About 59 adults will receive the drug before surgery. The main goa…
Matched conditions: EARLY-STAGE BREAST CANCER
Phase: PHASE4 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Could freezing breast cancer replace the knife? major trial launches
Disease control Not yet recruitingThis study compares freezing breast tumors (cryoablation) to standard surgery (lumpectomy) in women over 60 with early-stage, hormone-positive breast cancer. The goal is to see if cryoablation can control the disease just as well, with fewer side effects. About 938 participants w…
Matched conditions: EARLY-STAGE BREAST CANCER
Phase: PHASE3 • Sponsor: Franciscus Gasthuis & Vlietland (Hospital) • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Blood test may guide breast cancer therapy, reducing chemo need
Disease control Not yet recruitingThis phase 2 trial tests a personalized approach for early-stage, hormone receptor-positive breast cancer. Participants receive a combination of CDK4/6 inhibitors and endocrine therapy before surgery. A blood test (ctDNA) is used to monitor tumor DNA and may help decide if chemot…
Matched conditions: EARLY-STAGE BREAST CANCER
Phase: PHASE2 • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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Could a simple shave improve breast cancer surgery?
Disease control Not yet recruitingThis study looks at whether taking a thin layer of tissue from around the removed tumor (cavity shaving) is a safe and effective way to ensure all cancer is removed during breast-conserving surgery. It compares this method to the standard frozen section analysis. The goal is to s…
Matched conditions: EARLY-STAGE BREAST CANCER
Phase: NA • Sponsor: Mark Ezzat Gerges • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New hope for breast cancer survivors: drug may restore lost libido
Symptom relief Not yet recruitingThis study looks at whether adding the drug bupropion (Wellbutrin) to standard hormone therapy can help women with early-stage breast cancer who have lost interest in sex. About 100 women will be randomly assigned to receive either their usual hormone therapy alone or with buprop…
Matched conditions: EARLY-STAGE BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Exercise may ease side effects of breast cancer treatment
Symptom relief Not yet recruitingThis Spanish trial tests whether a 6-month exercise program (combining resistance and aerobic training) can improve quality of life in 74 early breast cancer patients taking hormone therapy. Half the participants will do the exercise program three times a week, while the other ha…
Matched conditions: EARLY-STAGE BREAST CANCER
Phase: NA • Sponsor: Spanish Breast Cancer Research Group • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC