CROHN DISEASE (CD)

This study is testing whether a specific probiotic (Clostridium butyricum) or a sugar supplement (trehalose) can help reduce scarring and inflammation in the intestines of people with a narrowing form of Crohn's disease. Forty participants will take one of these supplements or a …

This early-stage study is testing a new cell therapy called CNK-UT009 in patients with severe inflammatory bowel disease (Crohn's or colitis) who haven't responded to multiple other treatments. The main goal is to check if the treatment is safe and determine the right dose. Resea…

This study is testing whether the medication mirikizumab can achieve deep healing of intestinal inflammation in people with active Crohn's disease. It will involve 110 adult participants who have symptoms and visible inflammation on an MRI scan. The main goal is to see if 24 week…

This study is testing if a specific diet plan can make a standard Crohn's disease medication work better for children. Researchers will compare children taking the drug alone to those who also follow the special diet. The goal is to help kids achieve better disease control, reduc…

This study aims to see if an MRI scan for Crohn's disease works just as well without requiring patients to drink a special liquid that distends their bowels, a process many find unpleasant. Researchers will compare two MRI scans—one with the standard drink and one without—in 60 a…

This study is testing if a medication called modafinil can help reduce severe, long-term fatigue in people with Crohn's disease or ulcerative colitis. It's a small, early-stage trial to see if a larger study is possible. About 70 participants will be randomly assigned to take eit…

This study aims to create a tool to predict who might develop Crohn's disease. It will follow 10,000 healthy relatives of people with Crohn's across Europe. Researchers will use blood tests and regular questionnaires about health and lifestyle to build a risk score.

This study aims to learn how different diets and digital information tools affect inflammation and eating habits in people with Crohn's disease or ulcerative colitis. Researchers will compare 140 patients trying a special Nordic diet or using a digital tool against those receivin…

This study aims to improve MRI scans for Crohn's disease by analyzing tissue removed during surgery. Researchers will perform detailed scans on 60 intestinal specimens to create a precise map of inflammation and scarring. The goal is to validate new scan measurements that could o…

This study aims to understand if people with Crohn's disease or ulcerative colitis take daily Vitamin D supplements as recommended by their doctors. Researchers will follow 150 patients for one year to see how many stick with the supplement, if it improves their quality of life, …

This study aims to develop a tool to predict if inflammatory bowel disease (IBD) treatments will work for a patient. Researchers will give patients fluorescent versions of two common IBD drugs and use special cameras to see where the drugs go in the gut. The goal is to understand…

This study aims to see if data from wearable devices, grocery shopping habits, and patient surveys can be used to predict flare-ups in people with Crohn's disease or ulcerative colitis. Researchers will enroll 80 adults with IBD who are willing to use a smartphone, activity track…

This study aims to listen to patients with a specific form of Crohn's disease to understand their most important symptoms and how the disease affects their daily life. Researchers will conduct one-on-one interviews with 15 adults who have stricturing Crohn's disease. The goal is …