CROHN DISEASE (CD)

This study is testing a new device called SEGER IDEA™ that helps surgeons close openings in the bowel during keyhole surgery. It is the first time this device is being used in humans. Ten adults having certain types of bowel surgery will take part. The main goal is to see if the …

This study tested whether taking tempeh powder (a source of isoflavones) and vitamin D3 daily for 8 weeks could improve vitamin D levels, reduce inflammation, and boost quality of life in people with inflammatory bowel disease (IBD). Fifty adults with ulcerative colitis or Crohn'…

This study followed 150 people with inflammatory bowel disease (ulcerative colitis or Crohn's disease) who were given VedAryo (vedolizumab) to see if it helps control their condition and is safe. Participants received the drug by IV at the start, after 2 weeks, after 6 weeks, and…

This completed trial tested whether four free self-help resources—a symptom-tracking app, a cognitive behavioral therapy workbook, a helpline, and a peer mentor—can reduce disability in people with moderate-to-severe Crohn's disease or ulcerative colitis. Over 800 adults particip…

This study analyzed data from 500 Crohn's disease patients to create a tool that uses routine blood tests to predict the risk of needing intestinal surgery. The goal is to help doctors move from reacting to problems to preventing them. The model is still in early development and …

This study measured how often adults with inflammatory bowel disease (Crohn's disease or ulcerative colitis) show signs of eating disorders, including avoidant/restrictive food intake disorder (ARFID). Researchers used questionnaires to assess eating habits and nutritional status…

This study looked at 366 adults referred for suspected inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. The goal was to find simple, non-invasive markers that can help doctors diagnose IBD more accurately and predict how the disease will progres…

This study measured calprotectin, a protein in stool that signals gut inflammation, in 121 healthy adults aged 22 and older. Participants collected a single stool sample at home and mailed it in. The goal is to establish what level is normal, helping doctors better tell apart inf…

This completed study looked at whether differences in the IL-7 receptor gene are linked to the risk of developing Crohn's disease and how well patients respond to the drug infliximab. Researchers analyzed genetic samples from 303 Crohn's patients and 514 healthy people. The goal …