Could a probiotic help prevent gut scarring in Crohn's disease?

NCT ID NCT07263880

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether a probiotic called Clostridium butyricum can help prevent or treat scarring in the gut caused by Crohn's disease. About 40 adults with a narrowing form of Crohn's will take the probiotic, a sugar called trehalose, both, or a placebo for two months before a colonoscopy. Researchers will check tissue and blood samples for signs of reduced inflammation and scarring.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • San Giovanni Addolorata Hospital

    Roma, 00184, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••