COLORECTAL CARCINOMA
Clinical trials for COLORECTAL CARCINOMA explained in plain language.
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New registry maps how targeted liver treatment is used in colorectal cancer
Disease control CompletedThis registry followed 152 patients with colorectal cancer that had spread mainly to the liver. Doctors used tiny beads called LifePearl Microspheres loaded with the chemotherapy drug irinotecan, delivered directly to the liver's blood supply. The goal was to see how and when thi…
Matched conditions: COLORECTAL CARCINOMA
Sponsor: Cardiovascular and Interventional Radiological Society of Europe • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New combo therapy shows promise for Tough-to-Treat colon cancer
Disease control CompletedThis early-phase study tested a combination of two drugs, cabozantinib and TAS-102, in 15 people with advanced colorectal cancer that had spread and stopped responding to standard treatments. The main goal was to find the safest dose and identify side effects. The study is comple…
Matched conditions: COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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First human trial of BI 765049 combo aims to fight hard-to-treat cancers
Disease control CompletedThis early-phase study tests two experimental drugs, BI 765049 and ezabenlimab, in adults with advanced solid tumors like colorectal, lung, and pancreatic cancer. The main goal is to find the highest safe dose of BI 765049 alone and in combination with ezabenlimab. Participants r…
Matched conditions: COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Liver pump chemo shows promise for colorectal cancer that spread
Disease control CompletedThis study tested a special pump placed under the skin that sends chemotherapy directly to the liver through the hepatic artery. It was for people with colorectal cancer that had spread to the liver and who had already tried other chemotherapies. The goal was to see if this direc…
Matched conditions: COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New cocktail of cancer drugs tested for Tough-to-Treat colorectal cancer
Disease control CompletedThis study tested a combination of nivolumab (Opdivo) and trametinib (Mekinist), with or without ipilimumab (Yervoy), in 325 people whose colorectal cancer had spread and had not responded to prior treatments. The main goals were to check safety and see if the drugs could shrink …
Matched conditions: COLORECTAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Texting your way to better health: study tests SMS diet coach for cancer survivors
Symptom relief CompletedThis study tested whether sending personalized text messages could help colorectal cancer survivors eat more whole grains and less refined grains. Forty-six survivors who had finished active treatment received text messages and nutrition materials. The main goal was to see if peo…
Matched conditions: COLORECTAL CARCINOMA
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Rural cancer survivors test DIY care plans and phone education
Knowledge-focused CompletedThis study looked at whether cancer survivors living in rural areas can create their own survivorship care plans and learn from telehealth education. 261 survivors of breast, colorectal, lung, lymphoma, or prostate cancer took part. The goal was to see if this approach improves t…
Matched conditions: COLORECTAL CARCINOMA
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Tiny particles in blood may help detect hidden cancer spread
Knowledge-focused CompletedThis study looked at tiny particles called microparticles in the blood of 41 people with colorectal cancer that had spread to the lining of the abdomen. The goal was to see if these particles could serve as a better way to detect this spread early, compared to current tests. Rese…
Matched conditions: COLORECTAL CARCINOMA
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Can we map a Tumor's genes fast enough to help patients?
Knowledge-focused CompletedThis pilot study tested whether advanced genetic sequencing of tumors can be done quickly enough to guide treatment decisions. Researchers took blood and tumor samples from 24 adults with advanced soft-tissue sarcoma or metastatic colorectal cancer. They measured how long it took…
Matched conditions: COLORECTAL CARCINOMA
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:40 UTC